TABLE 4.
Genotypes, viral load, and amino acid substitutions in the VP1 region of BKV isolates from urine of controls.
|
Amino acid substitution a |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | Genotype | Viral load b | BC loop | β-C | β-D | DE loop | β-E | EF loop | β-F |
| 1 | I | 3,95E+05 | - | - | - | - | - | D175E V210I |
- |
| 2 | II | 3,54E+08 | - | - | - | E138Q | - | - | - |
| 3 | I | 2,97E+10 | - | - | - | - | - | - | - |
| 4 | IV | 6,93E+05 |
N61D D62N D77G |
- | - | - | V155I | E175D V178I I210V |
Y225F |
| 5 | IV | 3,24E+07 | D77E | - | - | - | - | - | - |
| 6 | I | 5,87E+06 | E82D | - | - | - | - | D175E V210I |
- |
| 7 | II | 3,95E+04 | - | L96P | K117Q |
N139H V145I |
- |
Q175D I210V |
Y225F |
a
amino acid numbers are those of Dunlop strain (Seif et al., 1979);
b
copies/ml; amino acid substitutions that cause a change of charge are underscored; β-C, β-D, β-E, β-F: β-sheets.