TABLE 5.
Frequency of amino acid substitutions detected in the VP1 region of BKV isolates from urine of PVAN patients and controls.
| Amino acid substitution a | Loop | Frequency | |
|---|---|---|---|
| PATIENTS | K69R, E73Q, D75N | BC | 1/8 |
| D77E, E82D | BC | 2/8 | |
| H139N | DE | 2/8 | |
| D175E, V210I | EF | 4/8 | |
| CONTROLS | N61D, D62N, D77G D77E, E82D | BC | 1/7 |
| L96P | β-C | 1/7 | |
| K117Q | β-D | 1/7 | |
| E138Q, N139H, V145I | DE | 1/7 | |
| V155I | β-E | 1/7 | |
| D175E, I210V, V210I | EF | 2/7 | |
| E175D, Q175D, V178I | EF | 1/7 | |
| Y225F | β-F | 2/7 | |
a
amino acid numbers are those of Dunlop strain (Seif et al., 1979).