Figure 1.

EM011 treatment suppresses microtubule dynamics in living cells. Time-lapse sequences, 3s apart, showing the plus-ends of several microtubules in LLCPK-1α cells in the absence (top row) and presence (bottom row) of 25 μM EM011. Arrows indicate three microtubules that are growing, and solid arrowheads indicate two microtubules that are undergoing shortening events. In the EM011-treated cell (bottom row), arrows indicate four microtubule ends for which the position did not change over a period of 12s.