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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Chem Rev. 2009 Oct;109(10):4644–4681. doi: 10.1021/cr900077w

Figure 12.

Figure 12

Proposed hydrogen bonding network in Zn(II)-bound CzrA that links the α5 regulatory sites to that of the DNA binding helices, which is thought to contribute directly to the magnitude of ΔGc (see Scheme 1).22,254