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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Chem Rev. 2009 Oct;109(10):4644–4681. doi: 10.1021/cr900077w

Figure 4.

Figure 4

Structure of a representative ABC importer, E. coli ModABC408 with the direction of transport shown by the red arrow. The green subunit ModA is the solute binding protein (SBP), with the position of the WO42− anion shaded red and highlighted in the gray circle. Other SBPs adopt a global structure similar to ModA but feature distinct metal coordination sites as shown for Fe(III)-, Zn(II)- and Mn(II)-specific SBPs (lower part of figure). Coordination sites are shown for the Fe(III)-specific SBP Campylobacter jejuni FbpA (1Y4T),93 a Zn(II) -SBP E. coli ZnuA (2OSV),410 the Mn(II)-SBP Synechocystis 6803 MntC (1XVL).122