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. Author manuscript; available in PMC: 2010 Nov 10.
Published in final edited form as: Neuroscience. 2009 Jul 24;163(4):1012–1023. doi: 10.1016/j.neuroscience.2009.07.040

Table 2.

Tissue concentrations of dopamine (DA), homovanillic acid (HVA), dihydroxyphenylacetic acid (DOPAC), serotonin (5-HT), 5-hydroxyindoleacetic acid (5-HIAA) of WT and En1+/Otx2 mutants. Values are reported as ng/mg tissue weight. Asterisks indicate significant difference in t testing (p<0.05).

Nucleus Accumbens
 Frontal Cortex
Substance WT En1+/Otx2 WT En1+/Otx2
DA 23.08 (10.19) 21.35 (7.78) 0.35 (0.19) 0.56 (0.31)
HVA 4.66 (1) 4.18 (1.64) 0.54 (0.15) 0.74 (0.21)
DOPAC 12.31 (4.03) 9.68 (6.28) 0.32 (0.08) 0.56 (0.18)*
5-HT 0.9 (0.40) 0.5 (0.18)* 0.79 (0.22) 0.26 (0.11)*
5-HIAA 1.32 (0.47) 0.62 (0.20)* 0.62 (0.31) 0.23 (0.07)*