. Author manuscript; available in PMC: 2010 Dec 1.

Published in final edited form as: J Biomed Inform. 2009 Jun 16;42(6):990–1003. doi: 10.1016/j.jbi.2009.05.010

Table 17.

The two novel interaction predictions shown in this table were supported by case reports but were not present in any of the 65 drug-drug interaction statements from product labeling that we had collected while building the validation set.

Predicted interaction	$DIKB \frac{{AUC}_{i}}{AUC}$	report and DIPS score
diltiazem - atorvastatin*	> 2	[63]:possible
fluconazole - simvastatin*	> 2	[64]:possible

Asterisks indicate the interaction’s predicted object drug.