Table 11.

The set of assertion types whose validity in the DIKB’s knowledge-base is based on evidence assessment. The assertion types are shown in decreasing order based on the number of LOEs that we defined for each of them.

Assertion type	LOE count
controls-formation-of	5
substrate-of	5
is-not-substrate-of	5
has-metabolite	4
primary-metabolic-clearance-enzyme	4
primary-total-clearance-enzyme	3
primary-total-clearance-mechanism	3
does-not-inhibit †	2
first-pass-effect †	2
fraction-absorbed †	2
inhibition-constant †	2
inhibits	2
maximum-concentration †	1
bioavailability †	1

^†An assertion type for which varying the LOE chosen as a belief criterion would have no effect on the DIKB’s prediction performance because all of the associated evidence was of a type belonging to the highest ranking LOE.