Table 1.
IC50s (nM) | |||
---|---|---|---|
Mutations | Nilotinib | Dasatinib | Sorafenib |
KIT502-503AY/V654A | 1045 | 334.5 | 1672 |
KITV560del/V654A | 192 | 585 | 1074 |
KIT502-503AY/D820Y | 248 | 40.6 | 842 |
KITV559D/D820Y | 297 | 432 | 944 |
KIT502-503AY/N822K | 369 | 66.2 | 933 |
KITV560del/N822K | NA | NA | NA |