Fig. 3.
AL does not disrupt conditioning in HSV-CREB mice established prior to viral transfection. (a) Schematic of the experimental design. (b) Histogram showing that AL infusion impairs CTA memory, which was generated after virus infusion (training after virus infusion). The aversion index (AI) is defined as follows: [milliliters of water consumed / (milliliters of water + milliliters of saccharin consumed)] ×100%. The higher the AI, the more the mice prefer water to saccharin and the better the CTA memory. Unpaired t test, *P < 0.05 as indicated. (c) AL had no effect on established tone fear memory (training before virus infusion). Pre-tone: freezing before tone presentation. Tone: freezing during tone presentation. n = 9 mice for AL group and n = 6 for VEH group.