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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Nat Neurosci. 2009 Sep 27;12(11):1438–1443. doi: 10.1038/nn.2405

Fig. 6.

Fig. 6

HSV-CREB changes the input-output function of transfected LA neurons. (a) Unit E-S curve of a HSV-CREB neuron and a neighboring non-transfected neuron (CON). Insert: representative EPSPs and action potentials traces from a HSV-CREB and a CON neuron following increasing synaptic stimulations. (b) Histogram showing that HSV-CREB lowers the inpu-output threshold in transfected LA neurons. The threshold was quantified as the EPSP slope (mVms−1) corresponding to 50% firing probability. (c) Histogram showing that HSV-CREB does not change the slope (Gain) of the linear component of the E-S curve. HSV-CREB, n = 10 and CON, n = 11 from 5 mice. Unpaired t test, *P < 0.01 as indicated.