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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Mol Aspects Med. 2009 Sep 1;30(6):490–502. doi: 10.1016/j.mam.2009.08.006

Table 1. Potential Anthrax Vaccine Strategies.

PA-based Vaccination Strategies
 First Generation (AVA)
 2nd Generation (PA102)
 3rd Generation (alternative rPA-based)
  Modified rPA
  Alternative adjuvants
  Needle-free delivery
   Intradermal injection
   Transcutaneous administration
  Mucosal administration
   Intranasal delivery
   Oral delivery (attenuated bacterial vector)
  Live, attenuated bacilli injection
  DNA vaccination
   Viral vector
   Plasmid injection
Alternative vaccination strategies
 Bacilli capsular antigens
 Attenuated whole spores
 Spore antigens
  BclA
  BxpB
  other
Passive antibody therapy
 Anti-PA
 Anti-LF
 Anti-capsule
 other