Table 2.
Library data for compounds 15{1–31}.
| compound | iminoalkyne | iodide | yielda (%) | purityb (%) |
|---|---|---|---|---|
| 15{1} | 11{1} | 14{1} | 41 | 94 |
| 15{2} | 11{1} | 14{2} | 39 | 93 |
| 15{3} | 11{1} | 14{3} | 45 | 86 |
| 15{4} | 11{1} | 14{4} | 60 | 92 |
| 15{5} | 11{1} | 14{5} | 36 | 92 |
| 15{6} | 11{1} | 14{6} | 87 | 99 |
| 15{7} | 11{1} | 14{7} | 51 | 91 |
| 15{8} | 11{1} | 14{8} | 47 | 93 |
| 15{9} | 11{1} | 14{9} | 28 | 93 |
| 15{10} | 11{1} | 14{10} | 40 | 90 |
| 15{11} | 11{1} | 14{11} | 48 | 91 |
| 15{12} | 11{2} | 14{2} | 24 | 91 |
| 15{13} | 11{2} | 14{3} | 24 | 88 |
| 15{14} | 11{2} | 14{4} | 18 | 90 |
| 15{15} | 11{2} | 14{6} | 14 | 98 |
| 15{16} | 11{2} | 14{10} | 23 | 95 |
| 15{17} | 11{2} | 14{12} | 27 | 90 |
| 15{18} | 11{2} | 14{13} | 11 | 94 |
| 15{19} | 11{3} | 14{1} | 72 | 96 |
| 15{20} | 11{3} | 14{3} | 30 | 88 |
| 15{21} | 11{3} | 14{4} | 50 | 86 |
| 15{22} | 11{3} | 14{6} | 43 | 91 |
| 15{23} | 11{3} | 14{7} | 44 | 95 |
| 15{24} | 11{3} | 14{8} | 27 | 94 |
| 15{25} | 11{3} | 14{10} | 30 | 93 |
| 15{26} | 11{3} | 14{12} | 50 | 90 |
| 15{27} | 11{3} | 14{13} | 32 | 87 |
| 15{28} | 11{1} | 14{3} | 71 | 93 |
| 15{29} | 11{1} | 14{11} | 55 | 77 |
| 15{30} | 11{1} | 14{14} | 57 | 75 |
| 15{31} | 11{1} | 14{15} | 26 | 87 |
a
Isolated yield after preparative HPLC.
b
UV purity determined at 214 nm after preparative HPLC.