Table 2.
Marker | Marker ID | Alleles (major) | Group | Genotypes (%) | Genotypic p-Value | Alleles (%) | Allelic p-Value | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
A1/A1 | A1/A2 | A2/A2 | F a | A1 | A2 | All | M | F | ||||
1 | rs11094547 | C/T (C) |
Cases | 63.9 | 15.8 | 20.2 | 0.18 | 78.0 | 22.0 | 0.18 | 0.15 | 0.57 |
Controls | 68.5 | 19.1 | 12.4 | 73.0 | 27.0 | |||||||
2 | rs12833553 | A/G (G) |
Cases | 79.8 | 11.8 | 8.4 | 0.21 | 85.2 | 14.8 | 0.23 | 0.61 | 0.27 |
Controls | 85.1 | 7.2 | 7.7 | 88.7 | 11.3 | |||||||
3 | rs6627221 | C/T (T) |
Cases | 72.2 | 15.0 | 12.8 | 0.47 | 80.4 | 19.6 | 0.089* | 0.13 | 0.31 |
Controls | 80.4 | 10.9 | 8.7 | 85.9 | 14.1 | |||||||
4 | rs2201169 | C/T (T) |
Cases | 76.9 | 13.4 | 9.7 | 0.38 | 83.0 | 17.0 | 0.088* | 0.27 | 0.19 |
Controls | 83.8 | 9.5 | 6.7 | 88.1 | 11.9 | |||||||
5 | rs11797836 | A/G (A) |
Cases | 83.9 | 11.5 | 4.6 | 0.46 | 88.5 | 11.5 | 0.37 | 0.66 | 0.20 |
Controls | 86.8 | 8.0 | 5.2 | 90.9 | 9.1 | |||||||
6 | rs5969896 | A/G (G) |
Cases | 82.4 | 11.9 | 5.7 | 0.90 | 88.2 | 11.8 | 0.71 | 0.27 | 0.70 |
Controls | 81.2 | 9.9 | 8.9 | 87.2 | 12.8 |
Because GABRA3 is located on the X chromosome, genotypic values are available only for females
p values that met the stage 1 screening threshold p < .1.