Table 4.
Stage 1 Association Results (N=188 cases, 188 controls) for GABRG2 (chromosomal band 5q34, length 87.9 Kb)
| Marker | Marker ID | Alleles (major) | Group | Genotypes (%) | Genotypic p-Value | Alleles (%) | Allelic p-Value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| A1/A1 | A1/A2 | A2/A2 | A1 | A2 | ||||||
| 1 | rs17060039 | C/T (T) |
Cases | 81.6 | 18.4 | 0 | 0.29 | 90.8 | 9.2 | 0.32 |
| Controls | 85.9 | 14.1 | 0 | 92.9 | 7.1 | |||||
| 2 | rs183294 | C/T (C) |
Cases | 40.7 | 43.4 | 15.9 | 0.47 | 65.9 | 34.1 | 0.31 |
| Controls | 43.4 | 45.1 | 11.5 | 62.4 | 37.6 | |||||
| 3 | rs209353 | C/T (T) |
Cases | 31.2 | 50.9 | 17.9 | 0.85 | 56.6 | 43.4 | 0.87 |
| Controls | 32.0 | 48.0 | 20.0 | 56.0 | 44.0 | |||||
| 4 | rs209358 | C/T (T) |
Cases | 34.1 | 44.7 | 21.1 | 0.76 | 56.4 | 43.6 | 0.79 |
| Controls | 33.3 | 48.1 | 18.6 | 57.4 | 42.6 | |||||
| 5 | rs211037 | C/T (C) |
Cases | 57.2 | 38.9 | 3.9 | 0.28 | 76.7 | 24.4 | 0.73 |
| Controls | 58.5 | 34.1 | 7.4 | 75.6 | 24.4 | |||||
| 6 | rs211032 | C/T (C) |
Cases | 47.2 | 42.2 | 10.6 | 0.46 | 68.3 | 31.7 | 0.28 |
| Controls | 51.1 | 41.8 | 7.1 | 72.0 | 28.0 | |||||
| 7 | rs210984 | G/T (T) |
Cases | 69.5 | 28.8 | 1.7 | 0.86 | 83.9 | 16.1 | 0.94 |
| Controls | 68.6 | 30.3 | 1.1 | 83.7 | 16.3 | |||||
| 8 | rs169793 | A/T (A) |
Cases | 32.9 | 47.2 | 19.9 | 0.29 | 56.5 | 43.5 | 0.11 |
| Controls | 39.9 | 45.2 | 14.9 | 62.5 | 37.5 | |||||
| 9 | rs17060106 | A/C (A) |
Cases | 71.7 | 26.7 | 1.6 | 0.95 | 85.0 | 15.0 | 0.77 |
| Controls | 70.1 | 28.3 | 1.6 | 84.2 | 15.8 | |||||
| 10 | rs12520992 | A/C (A) |
Cases | 73.1 | 23.6 | 3.3 | 0.86 | 84.9 | 15.1 | 0.57 |
| Controls | 75.6 | 21.6 | 2.8 | 86.4 | 13.6 | |||||
| 11 | rs211014 | A/C (C) |
Cases | 59.4 | 35.0 | 5.6 | 0.75 | 76.9 | 23.1 | 0.73 |
| Controls | 59.9 | 36.3 | 3.8 | 78.0 | 22.0 | |||||
| 12 | rs424740 | A/T (T) |
Cases | 36.7 | 52.8 | 10.5 | 0.16 | 63.1 | 36.9 | 0.67 |
| Controls | 39.3 | 44.4 | 16.3 | 61.5 | 38.5 | |||||