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. Author manuscript; available in PMC: 2010 Oct 28.
Published in final edited form as: J Am Chem Soc. 2009 Oct 28;131(42):15352–15357. doi: 10.1021/ja905854a
Pb2+-dependent DNAzyme:
17Eab 5′-ACAGACATCTCTTCTCCGAGCCGGTCGAAATAGXGAG-3′
17EG 5′-ACAGACATCTCTTCTCCGAGCCGGTCGAAATAGGGAG-3′
Substrate (a DNA/RNA chimer with a single RNA nucleotide linkage):
17S 3′-TGTCTGTAGAGAAGGrATATCCCTC-5′
Adenosine aptamer:
AAP 5′-TGTCGTTGACCTGGGGGAGTATTGCGGAGGAAGGT-3′
ssDNAs for hybridization with aptamer:
L1ab 3′-AGCAACTGXACC-5′
L2ab 3′-AGCAACTGXACCC-5′
L3ab 3′-AGCAACTGXACCCC-5′
L4ab 3′-ACAGCAACTGXACCCC-5′
L2G 3′-AGCAACTGGACCC-5′