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. Author manuscript; available in PMC: 2010 Jul 23.
Published in final edited form as: RNA Biol. 2009 Sep 23;6(4):412–425. doi: 10.4161/rna.6.4.8830

Table 1.

The studies on genetic variants related to miRNAs in humans

Discoveries of genetic variants related to miRNAs Reference
10 SNPs in miRNA precursors 24
339 SNPs in conserved seed-matching regions of target gene 25
483 SNPs in conserved seed-matching regions of target gene 26
1 SNP in the seed-matching region of target gene 27
A database with 22758 SNPs in the miRNA target sites or with potential ability to creat novel miRNA target sites 28
12 SNPs in miRNA precursors 29
1 SNP in the seed-matching region of target gene 30
About 400 SNPs in the miRNA target sites; 250 SNPs with the potential ability to creat novel miRNA target sites 31
265 SNPs in the miRNA target sites 32
79 SNPs in the seed-matching regions of target genes; 7 SNPs in miRNA precursors; 1 SNP in the mature miRNA 33
57 SNPs in the seed-matching regions of target genes 15
1 SNP in the seed-matching region of target gene 8
A joint database with SNPs in the miRNAs and their targets 35
One SNP (rs11614913) in hsa-mir-196a2 9, 20
One functional SNP in a miRNA target site. 16
41 genetic variations in 26 microRNA-related genes. 22
One SNP in a let-7 microRNA complementary site. 21
23 SNPs in 11 genes in the miRNA biogenesis pathway, 7 SNPs in 7 pre-miRNAs, and 10 SNPs in 8 pri-miRNAs 74
One SNP (rs2910164) in pre-miR-146a 18, 19
27 SNPs in hairpin structures of pre-miRNAs 36
188 SNPs in the miRNA precursors; 497 consensus SNPs in the seed-matching regions of target genes; 385 CNVs harboring miRNA precursors; 9 CNVs covering important miRNA processing genes. Present study