Table 1.
The studies on genetic variants related to miRNAs in humans
| Discoveries of genetic variants related to miRNAs | Reference |
|---|---|
| 10 SNPs in miRNA precursors | 24 |
| 339 SNPs in conserved seed-matching regions of target gene | 25 |
| 483 SNPs in conserved seed-matching regions of target gene | 26 |
| 1 SNP in the seed-matching region of target gene | 27 |
| A database with 22758 SNPs in the miRNA target sites or with potential ability to creat novel miRNA target sites | 28 |
| 12 SNPs in miRNA precursors | 29 |
| 1 SNP in the seed-matching region of target gene | 30 |
| About 400 SNPs in the miRNA target sites; 250 SNPs with the potential ability to creat novel miRNA target sites | 31 |
| 265 SNPs in the miRNA target sites | 32 |
| 79 SNPs in the seed-matching regions of target genes; 7 SNPs in miRNA precursors; 1 SNP in the mature miRNA | 33 |
| 57 SNPs in the seed-matching regions of target genes | 15 |
| 1 SNP in the seed-matching region of target gene | 8 |
| A joint database with SNPs in the miRNAs and their targets | 35 |
| One SNP (rs11614913) in hsa-mir-196a2 | 9, 20 |
| One functional SNP in a miRNA target site. | 16 |
| 41 genetic variations in 26 microRNA-related genes. | 22 |
| One SNP in a let-7 microRNA complementary site. | 21 |
| 23 SNPs in 11 genes in the miRNA biogenesis pathway, 7 SNPs in 7 pre-miRNAs, and 10 SNPs in 8 pri-miRNAs | 74 |
| One SNP (rs2910164) in pre-miR-146a | 18, 19 |
| 27 SNPs in hairpin structures of pre-miRNAs | 36 |
| 188 SNPs in the miRNA precursors; 497 consensus SNPs in the seed-matching regions of target genes; 385 CNVs harboring miRNA precursors; 9 CNVs covering important miRNA processing genes. | Present study |