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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Nat Genet. 2009 Oct 4;41(11):1238–1242. doi: 10.1038/ng.465

Figure 3. SOX2 can transform FOXE1- or FGFR2IIIb-expressing immortalized tracheobronchial epithelial cells.

Figure 3

A) Soft agar colony formation for AALE tracheobronchial epithelial cells expressing either SOX2, FOXE1 or the combination of factors. Graph shows number of colonies (+/− standard deviation of experiment) with p-values labeled with asterisks as in Figure 2. Also pictured are representative soft-agar images and immunoblots showing expression of Sox2 and FoxE1. B) Soft agar colony formation data (+/− standard deviations), immunoblots and representative soft-agar images from co-transformation assays in AALE cells with SOX2 and FGFR2 IIIb and FGFR2 IIIc ectopic expression.