Figure 3.
Fluorescence Intensity and number of molecules/microbubble based on FACSCalibur data of microbubbles conjugated with Alexa 647-MVCAM.A(429). (A) Fluorescence histograms of microbubbles conjugated with fluorescent antibody at the indicated concentrations (μg/107 microbubbles). Results from calibration beads were used to calculate the number of fluorescent molecules attached to the surface of microbubbles. (B) Table shows results of molecules/microbubble with respect to the fluorescent antibody concentration and microbubbles were incubated with. (C) MVCAM.A(429) site density per microbubble as a function of antibody concentration (μg/107 microbubbles). Background fluorescence values were subtracted from results; n=4, MFI –mean fluorescence intensity.