Table 2. Summary of the global gene p-values, permutation test, and False Disvory Rate for all genes with a permutation p ≤ 0.05.

Gene	# SNPs	p-value for most signifcant SNP*	permutation p - value for gene*	False Discovery Rate
PTEN	2	<0.0001	0.0001	0.019
POLB	3	0.00010	0.00040	0.076
ARNT	9	0.00040	0.0018	0.22
IFNGR1	2	0.0023	0.0070	0.58
RGS5	1	0.0073	0.0092	0.58
ROS1	7	0.0012	0.0098	0.58
MX1	7	0.0020	0.015	0.58
AMACR	6	0.0026	0.016	0.58
CFH	5	0.0042	0.020	0.58
IL12A	1	0.018	0.022	0.58
TERF1	5	0.0052	0.026	0.58
SLC23A1	3	0.0084	0.027	0.58
BAX	1	0.027	0.031	0.58
NQO1	2	0.026	0.031	0.58
PARP1	6	0.0064	0.032	0.58
MBL2	9	0.0037	0.033	0.58
LIPC	10	0.0035	0.036	0.58
CAV1	3	0.012	0.041	0.58
SCUBE2	3	0.013	0.044	0.58
ESR1	6	0.0072	0.047	0.58
PLK1	1	0.043	0.047	0.58
XRCC3	2	0.023	0.048	0.58

^*Adjusted for age (<55 years, ≥55 years), sex, smoking (0 pack-years, 0< pack-years <25, ≥25 pack-years), and lifetime coal use (<130 tons, ≥130 tons)