Table 5.

Patients Treated with Additional PH Medications After Initiation of Sildenafil

Patient	Medication(s) Added	Reason for Medication	Days After Sildenafil Initiation	Days of Medication Use	Remained on drug at latest follow-up
1	Bosentan	Sildenafil intolerance	950	155	Yes
2	CCB	Lack of echocardiogram improvement	75	269	Yes
3	Epoprostenol	Lack of echocardiogram improvement	18	10	No
4	CCB	Systemic hypertension	66	66	Yes
5	Bosentan	Lack of echocardiogram improvement	108	490	No
6	Bosentan	Lack of echocardiogram improvement	129	112	Yes
7	Epoprostenol	Lack of echocardiogram improvement	16	28	No
	Bosentan	Lack of echocardiogram improvement	56	191	Yes

PH = pulmonary hypertension; CCB = calcium channel blocker