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Plasma Aldosterone and Renal Function in sRen−/− and sRen+/+ Mice
| Genotype | PAC (pg/mL) | UOsm (mOsm/kg) | UOsm (mOsm/d) | UV (mL/d) | UNa(mM) | UK(mM) | UNa(mEq/d) | UK(mEq/d) |
|---|---|---|---|---|---|---|---|---|
| +/+ (n=3) | 694±70 | 3295±496 | 4.4±0.6 | 1.4±0.3 | 359±18 | 231±57 | 0.5±0.1 | 0.4±0.1 |
| −/− (n=4) | 933±51* | 634±117* | 5.0±0.5 | 9.0±2* | 85±17* | 62±12* | 0.7±0.1 | 0.5±0.1 |
PAC, Plasma aldosterone concentration; UOsm, Urine osmolality; UV, Urine volume; UNa, Urinary sodium; UK, Urinary potassium.
