Virologic failure |
Failure/viremia, documented resistance, therapy intensification |
Poor adherence |
Self discontinued, poor adherence, therapy simplification, self administration of regimen taken in the past |
Toxicities |
|
GI related |
Nausea/vomiting, diarrhea, pancreatitis, hepatitis/liver failure, lactic acidosis, abdominal pain, constipation, anorexia, belching, abdominal bloating, difficulty swallowing, GI bleeding, rectal bleeding |
Neurologic/non-psychiatric |
Headache, sedation, insomnia, stumbling gait, peripheral neuropathy, dizziness/vertigo |
Constitutional |
Arthralgias, fever/chills, cough, weight loss/cachexia, fatigue, malaise/lethargy, myalgias/muscle pain, edema, night sweats, back/flank pain, lymphadenopathy, chest pain, asthenia/weakness |
CNS related/Psychiatric |
Hypomania, anxiety/stress, depression, vivid dreams, altered mental status/delirium, mental disorder |
GU related |
Renal failure, nephrolithiasis, proteinuria, urinary dysfunction |
Metabolic/Endocrine |
Lipodistrophy, fat redistribution, increased lipids, increased glucose, breast enlargement, hypophosphatemia |
Dermatologic |
Rash, injection site itching/nodules, alopecia, angioedema, flushing |
Hematologic |
Anemia, leucopenia/neutropenia |
Other medical condition/drug interaction |
Pneumonia, hospitalized, improving from previous medical condition caused by drugs, drug abuse/substance abuse, myocardial infarction, upper respiratory infection, erectile dysfunction, concomitant illness, congestive heart failure, meningitis, pregnancy, delivery of child |