Table 1.

Patient Characteristics

Characteristic	Men		Women		P
Smoking Status at Diagnosis	N	%	N	%
Never Smokers	1	2.5%	5	31.3%	0.002a
Former Smoker	20	50.0%	2	12.5%
Active Smokers	18	45.0%	9	56.3%
Unknown	1	2.5%	0	0.0%
Total	40		16
Pack-years	Years		Years
Median (Range)	64#		26.2#		0.06b
Age	Years		Years
Median	61		56.5		0.17b
Range	42-79		23-80
Tumor Site	N	%	N	%
Oral Cavity	16	40.0%	7	43.8%	0.62a
Oropharynx	6	15.0%	4	25.0%
Hypopharynx	2	5.0%	0	0.0%
Larynx	15	37.5%	4	25.0%
Cervical Lymph Node	1	2.5%	1	6.3%
Total	40		16
Disease Stage	N	%	N	%
I	3	7.5%	1	6.3%	0.42a
II	6	15.0%	5	31.3%
III	4	10.0%	3	18.8%
IV	22	55.0%	5	31.3%
Not Staged	5	12.5%	2	12.5%
Total	40		16
Adjuvant Therapy	N	%	N	%	0.11a
RT Only	11	28.2%	9	56.3%
CT Only	0	0.0%	0	0.0%
RT Plus CT	7	17.9%	3	18.8%
No RT or CT	21	53.8%	4	25.0%
Total	39		16
Disease Progression	N	Months	N	Months
Progression##	25		8		0.22c
No Progression	15		8
Median (Range)		17.9 (1.2-81)		32 (2.7-78.3)

^#Pack-year smoking data were available for 33 male and 16 female subjects

^##Progression defined as new HNSCC, recurrent HNSCC, metastases or death

^aFisher’s exact test

^bRank sum test

^cLog rank test