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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Jul 23;1789(9-10):518–528. doi: 10.1016/j.bbagrm.2009.07.004

Figure 4. Schematic representation of the common structural core in IRES elements of cellular mRNAs (A) and IRES elements of picornavirus, HCV, and pestivirus (B).

Figure 4

Stems A and E are shown as including an internal loop. The potential unpaired nucleotides in stems B-D and stems F-J are not shown. Stems A-D in the structural core of the cellular IRES correspond to stems E-I/J in the viral IRES core. (Figure reproduced and modified from Le and Maizel, 1997, with permission [87]).