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. Author manuscript; available in PMC: 2010 Dec 3.
Published in final edited form as: J Control Release. 2009 Aug 20;140(2):134–140. doi: 10.1016/j.jconrel.2009.08.008

Scheme 1.

Scheme 1

Synthesis of graft copolymers: PPAA-g-PEO and PPAA-g-Jeffamine. A fraction of the carboxylic acid groups on the PPAA backbone were reacted with the end group of PEO/Jeffamine chains to form ester/amide bonds, respectively.