Table 3.
Mean trial initiation latency, mean pellet retrieval time and the number of premature responses per trial in rats repeatedly treated with MPH (n=17) or SAL (n=12) following an acute challenge administration of mph (0.33 mg/kg) or sal (1ml/kg). Acute treatments were delivered 30 min prior to testing .Data are expressed as mean ± sem
Group | Acute challenge | Mean Trial Initiation Latency (s) | Mean Pellet Retrieval Time (s) | Tot Premature/Tot Trials | |
---|---|---|---|---|---|
Retention | Reversal | ||||
SAL | sal | 3.39 ±0.36 | 3.15 ±0.37 | 1.27 ±0.04 | 0.85 ±0.19 |
mph | 4.10 ±0.39** | 4.58 ±0.33** | 1.30 ±0.04 | 0.81 ±0.16 | |
MPH | sal | 2.99 ±0.35 | 3.11 ±0.38 | 1.26 ±0.03 | 0.79 ±0.09 |
mph | 3.91 ±0.42* | 4.20 ±0.43** | 1.30 ±0.04** | 0.66 ±0.09 |
p≤0.05
p≤0.01: significant difference between sal and mph.