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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Exp Hematol. 2009 Oct 6;37(12):1411–1422. doi: 10.1016/j.exphem.2009.09.009

Figure 4. Analysis of RAS and PI3-Kinase pathway activation signatures.

Figure 4

Gene expression signatures of oncogenic signaling pathways to characterize the activation status of RAS and PI3-kinase pathways were applied to data from patients with PV and healthy controls. The probability of PI3-kinase (panels on left) and RAS pathway (panels on right) deregulation in PV erythroblasts are significantly increased compared to normal control erythroblasts.