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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: FEMS Microbiol Lett. 2009 Sep 17;301(1):1–11. doi: 10.1111/j.1574-6968.2009.01791.x

Fig. 4.

Fig. 4

Histopathological changes in the lungs of mice infected by the i.n. route with a minimum lethal dose of type A F. tularensis KU49. Note the perivascular and peribronchial pyogranulomatous infiltrates on day 3 and day 4 and the extensive cell death (TUNEL) seen on day 4 p.i. Most of the cells in areas of cell death and necrosis bear the surface marker Ly-6G. The F4/80 cell surface marker was present on only a few infiltrating cells. Bars, 100 μm.