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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Infect Dis. 2009 Dec 1;200(11):1685–1693. doi: 10.1086/646616

Figure 5. Increased AOAH expression shortens recovery time from LPS challenge.

Figure 5

Mice were injected i.p. with 10 μg of E.coli O14 LPS and bled 1 hr (A) or 4 hrs (B) later to measure serum TNF-α and IL-6, respectively. (C) E.coli O14 LPS (10 mg/kg body weight) was injected i.p into wildtype and transgenic mice. Mice were weighed daily for 7 days. *p <0.05, **p<0.01 (Student’s t-test). Data are combined from two experiments, n=9/group. (D) Constitutive overproduction of AOAH does not protect mice from a non-LPS agonist. Weights were monitored daily for 7 days after i.p. injection of 1mg/kg UT 12 antibody. Data were combined from two independent experiments, each with n = 4. WT = wild-type; TG = AOAH transgenic.