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Frequency plots of genomic copy number gains and losses in pleomorphic lobular carcinoma in situ (PLCIS) and classic LICS (CLCIS). The proportion of LCIS lesions in which each BAC clone is gained (green) or lost (red) is plotted on the y axis according to its genomic location on the×axis. Vertical dotted lines represent chromosome centromeres. A: CLCIS (N=20); B: PLCIS (N=21); C: Non-apocrine PLCIS (N=13); D: Apocrine PLCIS (N=8).
