Table III.
Adjusted Associations Estimated as Odds Ratios (OR) of Infant Wheezing with Demographic and Environmental Factors.
| Wheezing at 12 Months | Wheezing at 24 Months | Persistent Wheezing | |||||||
|---|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
| Male Gender | 1.47 | 0.97–2.23 | 0.07 | 1.92 | 1.16–3.17 | 0.01 | 2.13 | 1.15–3.97 | 0.02 |
| Non-Caucasian Race | 1.20 | 0.69–2.07 | 0.52 | 2.54 | 1.36–4.75 | 0.00 | 2.91 | 1.36–6.21 | 0.01 |
| Daycare Attendance* | 1.88 | 0.91–3.91 | 0.09 | 1.81 | 0.95–3.47 | 0.07 | 1.36 | 0.66–2.79 | 0.41 |
| DEP Estimate Exposure ≥ 0.50 µg/m3 | 0.92 | 0.40–2.14 | 0.85 | 1.93 | 1.06–3.53 | 0.03 | 2.13 | 1.03–4.41 | 0.04 |
| ETS Exposure | 1.73 | 1.11–2.70 | 0.02 | 1.90 | 1.13–3.18 | 0.02 | 1.49 | 0.76–2.81 | 0.22 |
| Mold Exposure | 1.22 | 0.79–1.86 | 0.37 | 2.12 | 1.25–3.60 | 0.01 | 2.47 | 1.27–4.80 | 0.01 |
| Ile/Val or Val/Val GST-P1 Genotype | 0.94 | 0.59–1.47 | 0.77 | 1.25 | 0.76–2.07 | 0.38 | 0.94 | 0.52–1.73 | 0.85 |
| Ile/Val or Val/Val GST-P1*DEP Estimate ≥ 0.50µg/m3 | 2.09 | 0.69–6.30 | 0.19 | ns | ns | ||||
Defined as daycare attendance during the first year of life for wheezing at age 12 months, attendance during the second year of life for wheezing at 24 months of age and lifetime attendance for persistent wheezing.
ns: not significant at the 0.20 level and therefore removed from model (interaction only).
ETS, mold and/or high DEP
ref: referent category