Table 2.
Haemodynamic and oxygen transport in inotrope groups only. Values are median (interquartile range) unless stated otherwise
| Variable | Adrenaline group (n=46) | Dopexamine group (n=46) |
|---|---|---|
| Baseline: | ||
| Pulmonary artery occlusion pressure (mm Hg) | 12.0 (9.0-15.0) | 10.0 (8.0-12.0) |
| Cardiac index (ml/min/m2) | 3.2 (2.6-3.6) | 3.6 (2.9-4.1) |
| Oxygen delivery (ml/min/m2) | 530 (435-590) | 564 (486-636) |
| End fluid optimisation phase: | ||
| Fluid given (ml) | 1250 (1000-1500) | 1100 (875-1300) |
| Pulmonary artery occlusion pressure (mm Hg) | 14.0 (13.0-15.0) | 13.5 (12.0-15.0) |
| Cardiac index | 3.5 (2.8-4.0) | 3.8 (3.3-4.5) |
| Oxygen delivery | 541 (438-590) | 604 (521-686) |
| End inotrope optimisation phase: | ||
| No of increments | 1.0 | 1.0 |
| Pulmonary artery occlusion pressure (mm Hg) | 13.5 (11.0-15.0) | 13.0 (10.2-14.0) |
| Cardiac index | 4.7 (4.0-5.3) | 4.3 (3.8-4.8) |
| Oxygen delivery | 721 (638-827) | 665 (632-769) |
| Total fluid given (ml) | 1500 (1000-2000) | 1525 (1000-2000) |
| Duration of preoptimisation (minutes) | 276 (200-345) | 275 (214-331) |
| No of patients who failed to reach target oxgen delivery | 1 | 3 |
| No of patients with new dysrhythmias: | 4 | 1 |
| Ventricular ectopics | 2 | 0 |
| Ventricular tachycardia | 0 | 1 |
| Sinus tachycardia | 2 | 0 |
| Additional therapy: | ||
| Blood transfusion | 2 | 2 |
| Oxygen therapy | 8 | 5 |