Respiratory: |
Prolonged weaning |
1 |
3 |
1 |
Adult respiratory distress syndrome |
1 |
1 |
4 |
Pleural effusion |
3 |
3 |
2 |
Secondary ventilation |
6 |
4 |
8 |
Sputum retention |
4 |
1 |
5 |
Cardiovascular: |
Myocardial infarction |
4 |
2 |
3 |
New arrhythmia |
8 |
7 |
11 |
Cardiac arrest |
1 |
1 |
3 |
Pulmonary embolus |
1 |
1 |
2 |
Cerebrovascular accident |
0 |
0 |
1 |
Transient ischaemic attack |
1 |
0 |
0 |
Cardiac failure |
14 |
4 |
12 |
Gastrointestinal: |
Infarction of gastrointestinal tract |
1 |
0 |
1 |
Gastrointestinal haemorrhage |
0 |
0 |
4 |
Renal or metabolic: Acute renal failure |
2 |
0 |
3 |
Haematological or immune: Coagulopathy |
2 |
1 |
4 |
Infection: |
Bacteraemia |
2 |
0 |
2 |
Sepsis syndrome |
2 |
0 |
1 |
Septic shock |
0 |
2 |
0 |
Respiratory sepsis |
8 |
2 |
7 |
Urinary sepsis |
0 |
1 |
5 |
Abdominal sepsis |
2 |
0 |
2 |
Wound sepsis |
3 |
0 |
3 |
Line sepsis |
0 |
1 |
0 |
Other sepsis |
5 |
0 |
2 |
Surgical: |
Anastomotic breakdown |
0 |
0 |
3 |
Deep haemorrhage |
2 |
2 |
4 |
Wound haemorrhage |
3 |
0 |
2 |
Total |
87 |
44 |
109 |
No of patients with complications |
24 |
14 |
28 |
Proportion of patients |
0.52 |
0.30 |
0.61 |
Differences in proportions of patients with complications (95% CI): |
Dopexamine v control |
0.30 (0.11 to 0.50) |
Dopexamine v adrenaline |
0.21 (0.02 to 0.41) |
Adrenaline v control |
0.09 (−0.11 to 0.28) |
Actual morbidity (%) |
52 |
30 |
61 |
Predicted morbidity (%) |
54 |
61 |
57 |
Standardised morbidity ratio (95% CI) |
0.96 (0.62 to 1.44) |
0.50 (0.27 to 0.84) |
1.07 (0.71 to 1.54) |