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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Biomaterials. 2009 Sep 25;31(2):308–314. doi: 10.1016/j.biomaterials.2009.09.045

Figure 1.

Figure 1

Peptide-functionalized hydrogels formed by native chemical ligation. Prior to mixing 4-armed PEG-Cys (A) and 4-armed PEG-ThE (B) to form hydrogel, maleimide-terminated peptides are used to modify 1~5% cystine groups of PEG-Cys. The hydrogel resulting from NCL reaction between PEG-ThE and peptide modified PEG-Cys contains peptides covalently bound to the polymer network.