Table 1.
Demographic and Clinical Data in Stroke Subjects and Control Subjects in Study 1
| ISGS |
|||
|---|---|---|---|
| Discovery Phase | Cases | Control Subjects | P Value |
| No. of samples | 307 | 324 | |
| Age, median (SD) | 68.32 (14.67) | 65.04 (14.71) | 0.0096 |
| Gender (male), n (%) | 183 (60) | 124 (40) | 0.1085 |
| Hypertension, n (%) | 196 (64) | 124 (38) | <0.001 |
| Diabetes mellitus, n (%) | 77 (25) | 36 (11) | <0.001 |
| Smoking, n (%) | 217 (71) | 170 (52) | <0.001 |
| Heart disease, n (%) | 84 (27) | 42 (13) | <0.001 |
| ISGS |
Coriell |
SWISS |
|||||
|---|---|---|---|---|---|---|---|
| Replication Phase | Cases | Control Subjects | Cases | Control Subjects | Cases | Control Subjects | P Value* |
| No. of samples | 92 | 2 | 398 | 267 | 93 | 1 | |
| Age, median | 68.34 | 74.34 | 68.00 | 69.00 | 70.00 | 56.00 | <0.001 |
| SD | 15.34 | 9.60 | 14.08 | 8.78 | 10.45 | NA | |
| Gender (male), n (%) | 34 (37) | 1 (50) | 223 (56) | 175 (44) | 48 (52) | 1 (100) | 0.0149 |
| Hypertension, n (%) | 50 (54) | 1 (50) | 232 (59) | 78 (29) | 67 (72) | 1 (100) | <0.001 |
| Diabetes mellitus, n (%) | 16 (17) | 1 (50) | 58 (15) | 21 (8) | 27 (29) | 0 (0) | <0.001 |
| Smoking, n (%) | 55 (60) | 2 (100) | 235 (61) | 108 (40) | 91 (98) | 1 (100) | <0.001 |
| Heart disease, n (%) | 29 (32) | 1 (50) | 17 (4) | 31 (12) | 20 (22) | 0 (0) | 0.8182 |
*
P value showing differences between cases and control subjects.
NA indicates not applicable.