Figure 9.

The microanatomical proximity of migratory interneurons with L1⁺ and TAG-1⁺ axons. (A) PSA-NCAM⁺ migratory interneurons associated with L1⁺ axons in an E15.5 rat. (B) GAD67-GFP⁺ migratory interneurons in E13.5 mice in contact with L1⁺ axons. In both species, the bulk of migratory GABAergic interneurons exiting from the ganglionic eminences occupied a medial territory, where they overlapped with L1⁺ axons. A less dense population of migrating interneurons located more laterally also overlapped with L1⁺ axons. (C) GAD67-GFP⁺ migratory interneurons in E13.5 mice in contact with TAG-1⁺ axons. The sparse population of interneurons located at the lateral tier of the migratory path could associate with TAG-1⁺ axons, which accumulated below the subplate. Vertically oriented TAG-1⁺ axons and cell bodies in the cortical plate could interact with interneurons entering this compartment. Calibration bar: (A) 30 μm. (B,C) 50 μm.