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. Author manuscript; available in PMC: 2010 Nov 24.
Published in final edited form as: Biochemistry. 2009 Nov 24;48(46):10866–10881. doi: 10.1021/bi901476k

Table 5.

Polymerization of natural NTPs and iso-GTP opposite iso-C, 3-deazaadenine, and hypoxanthine. Listed is the concentration (μM) of the NTP that gives equal elongation of the ppp(G)3 trinucleotide with that NTP and with GTP. “ND” means no detectable incorporation

Triphosphate
graphic file with name nihms-154204-t0044.jpg graphic file with name nihms-154204-t0045.jpg graphic file with name nihms-154204-t0046.jpg graphic file with name nihms-154204-t0047.jpg
Template graphic file with name nihms-154204-t0048.jpg 100 ± 30 3000 ± 100 5900 ± 200 ND
graphic file with name nihms-154204-t0049.jpg 9 ± 3 11 ± 1 5000 ± 100 ND
graphic file with name nihms-154204-t0050.jpg 30 ± 20 23 ± 3 6300 ± 300 ND