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. Author manuscript; available in PMC: 2010 Nov 24.
Published in final edited form as: Biochemistry. 2009 Nov 24;48(46):10866–10881. doi: 10.1021/bi901476k

Table 6.

Polymerization of natural NTPs opposite pyrimidine analogues. Listed is the concentration (μM) of the NTP that gives equal elongation of the ppp(G)3 trinucleotide with that NTP and with GTP. “N” Dmeans no detectable incorporation

Triphosphate
graphic file with name nihms-154204-t0051.jpg graphic file with name nihms-154204-t0052.jpg graphic file with name nihms-154204-t0053.jpg
Template graphic file with name nihms-154204-t0054.jpg 1600 ± 100 1000 ± 100 4200 ± 400
graphic file with name nihms-154204-t0055.jpg 120 ± 5 870 ± 40 120 ± 20
graphic file with name nihms-154204-t0056.jpg 180 ± 20 ND ND
graphic file with name nihms-154204-t0057.jpg 1200 ± 50 ND 14000 ± 1000