Fig. 2.

Effect of LPS challenge on the consumption of ad lib sweetened milk solution and deionized water in experiment 1 (left panels A–C) and of restricted sweetened milk intake in experiment 2, where the intake was limited to approx. 5 g (right panels D–F). Bar graphs depict mean and SE; light and dark shading represent saline- and LPS-treated groups, respectively. Baseline intake during the days prior to treatment did not differ between the two treatment groups (A, D). LPS challenge is associated with a large reduction in sweetened milk intake in experiment 1 (B), and a smaller reduction of milk intake in experiment 2 (E). Panels C and F depict the percentage change in consumption that was calculated from the baseline and experimental day values of each individual rat. Both consumption of water and sweetened milk solution when offered ad lib dropped sharply (C), but the drop in intake of the sweetened milk solution was modest when the limited amount was offered (F). * p < 0.05, ** p < 0.005, LPS vs. saline treatment.: ## p < 0.005, sweetened milk vs. water exposure.