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. Author manuscript; available in PMC: 2009 Nov 26.
Published in final edited form as: Hepatology. 2009 Nov;50(5):1567–1576. doi: 10.1002/hep.23146

Figure 7.

Figure 7

Doxorubicin and retinoic acid modulate GJIC: role of HuR. WB-F344 cells were transfected with control or HuR-specific siRNA, followed by exposure to doxorubicin (A; 1 μM for 24 h) or all-trans-retinoic acid (B; RA, 1 or 10 μM for 24 and 48 h) and determination of GJIC. Data are given as means ± SD (n=3). ANOVA with Student-Newman-Keuls post-test was used for the determination of statistical significance between treatment groups. P < 0.05 was selected as the level of significance. Treatment groups are significantly different from each other if no labeling letter (a to e) is shared between groups.