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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Nat Cell Biol. 2009 Oct 4;11(11):1297–1304. doi: 10.1038/ncb1974

Figure 5.

Figure 5

KLF17 and Id1 expression in breast cancer cell lines and their predictive value of lymph node metastasis in human primary breast cancer samples. (A) KLF17 and Id1 expression in human breast cancer cells was determined by qRT-PCR. KLF17 expression is higher in non-invasive MCF7, MDA-MB-361 and CAMA cells, but lower in invasive MDA-MB-435, MDA-MB-436, MDA-MB-453 and MDA-MB-231 cells. Id1 expression is higher in invasive cells but lower in non-invasive cells. Pearson correlation analysis indicated that the expression of KLF17 and Id-1 was inversely correlated (r=-0.75, p=0.05). (B) KLF17 and Id1 expression are predictive markers of lymph node metastasis in human primary breast cancer samples. The receiver operating characteristic curves for KLF17 (left), Id-1 (middle) and the bivariate logistic regression model for KLF17 and Id1 (right).