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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Prog Biophys Mol Biol. 2009 Jun 11;100(1-3):47–56. doi: 10.1016/j.pbiomolbio.2009.06.004

Figure 5. One-parameter bifurcation diagrams for a double-negative feedback loop with multisite phosphorylation by an ordered (A) or disordered (B) distributive mechanism.

Figure 5

The steady state level of kinase (K) is plotted against the phosphatase activity (h) for different thresholds (q). Parameter values: κs = 0.02, κd = 0.02, κa = 0.98, XT = 1, N = 10.

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