Table 1.

Patient Characteristics

Variable	HNSCC cases with progression (n=15)	HNSCC cases without progression (n=16)	P
Age, y
Median (range)	66.6 (53.9, 81.0)	64.7 (45.1, 79.1)	0.64 (Wilcoxon)
Mean ± SD	66.2 ± 8.9	64.2 ±10.9	0.57 (t-test)
Gender, n (%)			0.70 (Fisher’s exact test)
Male	11 (73.3)	10 (62.5)
Female	4 (26.7)	6 (37.5)
Tobacco use at time of sample collection, n (%)			0.70
Current	4 (26.7)	6 (37.5)
Former	11(73.3)	10 (62.5)
Pack year exposure*
Median (range)	28.1 (2, 100.5)	25.0 (2.5, 80.0)	0.88
Mean ± SD	30.2 ± 28.6	28.2 ± 22.7	0.84
Tobacco use during follow-up, n (%)			0.23
Yes	2 (13.3)	0 (0)
No	13 (86.7)	16 (100)
Aspirin use before urine collection, n (%)			0.69
Yes	4 (26.7)	3(18.8)
No	11 (73.3)	13 (81.2)
Aspirin use during follow-up, n (%)			1.00
Yes	2 (13.3)	2 (12.5)
No	13 (86.7)	14 (87.5)

^*Excludes 1 pipe smoker in both groups