Skip to main content
. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Int J Pharm. 2009 Aug 5;382(1-2):222–233. doi: 10.1016/j.ijpharm.2009.07.030

Fig. 6.

Fig. 6

Fluorescence photomicrographs of tissue from an adult BALB/c mouse injected with doxorubicin, contained within liver-targeting liposomes, 1h prior to euthanasia. For each organ, the same tissue section is shown under rhodamine epifluorescence for doxorubicin (left column) and ultraviolet epifluorescence for DAPI nuclear labeling (right column). (A and B) Liver. (C and D) Heart. (E and F) Kidney. (G and H) Spleen. Note distinct red fluorescent doxorubicin labeling of cell nuclei in liver, but not heart or kidney. Doxorubicin labeling of cells in the marginal zone of spleen also is detected. cv: central vein; mz: marginal zone; wp: white pulp. Calibration bar in H = 100 μm and is the same for all photomicrographs.