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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Int J Pharm. 2009 Aug 5;382(1-2):222–233. doi: 10.1016/j.ijpharm.2009.07.030

Table 2.

Relative organ distribution of doxorubicin delivered as free doxorubicin vs. targeted liposomal doxorubicin

% of total in the 5 organs
Ratio:μgDoxpergliverμgDoxpergorgan

Organ free doxorubicin liposomal doxorubicin free doxorubicin liposomal doxorubicin
Heart 4.2 ± 0.7 % 0.07 ± 0.03 % 1.9 ± 0.7 171 ± 64
Kidney 18.9 ± 1.1 % 0.98 ± 0.27 % 1.0 ± 0.3 26 ± 8.1
Liver 71.5 ± 2.5 % 97.6 ± 0.6 % 1 1
Lungs 4.0 ± 0.7 % 0.07 ± 0.03 % 3.0 ± 1.4 163 ± 85
Spleen 1.5 ± 0.2 % 1.2 ± 0.3 % 5.0 ± 1.5 10 ± 4.1

Values are calculated from the data presented in Fig. 5., and are mean ± s.e.m, n=4.