Table 2.
% of total in the 5 organs |
|
||||
---|---|---|---|---|---|
Organ | free doxorubicin | liposomal doxorubicin | free doxorubicin | liposomal doxorubicin | |
Heart | 4.2 ± 0.7 % | 0.07 ± 0.03 % | 1.9 ± 0.7 | 171 ± 64 | |
Kidney | 18.9 ± 1.1 % | 0.98 ± 0.27 % | 1.0 ± 0.3 | 26 ± 8.1 | |
Liver | 71.5 ± 2.5 % | 97.6 ± 0.6 % | 1 | 1 | |
Lungs | 4.0 ± 0.7 % | 0.07 ± 0.03 % | 3.0 ± 1.4 | 163 ± 85 | |
Spleen | 1.5 ± 0.2 % | 1.2 ± 0.3 % | 5.0 ± 1.5 | 10 ± 4.1 |
Values are calculated from the data presented in Fig. 5., and are mean ± s.e.m, n=4.