Table 1.

Effects of Amphetamine and Dizocilpine across prepulse intensities.

	4 db	8 db	16 db
Male/Female Combined
Saline	38.99±2.68	51.8±3.06	62.59±2.93
Amph (1 mg/kg)	37.42±2.75	54.03±2.79	70.64±2.58
Amph (3 mg/kg)	17.77±2.73**	36.38±2.95**	61.38±2.42
Amph (10/mg/kg)	8.77±2.70**	25.50±3.17**	50.16±2.79**
Male
Saline	32.73±3.99	45.41±4.53	57.69±4.84
Dizocilpine (0.3 mg/kg)	12.54±3.27**	25.50±4.24**	52.28±3.60
Dizocilpine (1.0 mg/kg)	10.47±3.62**	19.38±3.31**	41.76±4.01*
Dizocilpine (3.0 mg/kg)	15.96±4.02**	24.67±3.90**	43.95±4.30
Female
Saline	39.21±3.79	52.15±3.92	62.72±3.80
Dizocilpine (0.3 mg/kg)	2.23±5.36**	34.83±4.34**	53.31±3.97
Dizocilpine (1.0 mg/kg)	9.53±3.38**	16.49±4.61**	36.47±5.32**
Dizocilpine (3.0 mg/kg)	12.18±2.68**	20.19±2.24**	37.81±4.04**

There was a significant Prepulse × Amphetamine interaction and a Prepulse intensity × Dizocilpine × Gender interaction. Therefore, male and female data are shown separately for dizocilpine but combined for amphetamine. Means ± SEM. Significantly different from saline at the same prepulse intensity with two tailed Dunnett’s post hoc tests, represented by

^*P < 0.05,

^**P < 0.01.