Fig. 2.

Genes with altered renal expression in systemic candidiasis form three distinct clusters. Differentially regulated genes in the kidneys of infected mice were analyzed by the Gene Tree function of Genespring to group genes regulated in a similar manner. Genes are colored by their fold regulation relative to control, as shown by the key on the right. K-means clustering separated the genes into three large clusters as numbered in the clusters column. Each column contains data from single microarray hybridizations, with V representing infection by the virulent strain and A representing infection by the attenuated strain.