Figure 4.

Topological roles of network nodes in intra- and inter-modular connectivity. (A) All nodes are plotted in the {P − z} plane of intra-modular degree z vs participation coefficient P; the solid lines partition the plane according to criteria for hubs vs non-hubs and connector, provincial, peripheral or kinless nodes. (B) Anatomical representation of the provincial hubs (circles), connector hubs (large squares) and connector nodes (small squares) of each of each of the five largest modules at the highest level of the modular hierarchy. (C) Topological representation of the network in using Fruchterman–Reingold algorithm (Fruchterman and Reingold, 1991) to highlight topological proximity of highly connected nodes; colour and shape of the nodes represent their modular assignment and topological role as above and in Figure 2.